Anti-inflammatory effects of ozenoxacin, a topical quinolone antimicrobial agent
نویسندگان
چکیده
منابع مشابه
Repurposing celecoxib as a topical antimicrobial agent
There is an urgent need for new antibiotics and alternative strategies to combat multidrug-resistant bacterial pathogens, which are a growing clinical issue. Repurposing existing approved drugs with known pharmacology and toxicology is an alternative strategy to accelerate antimicrobial research and development. In this study, we show that celecoxib, a marketed inhibitor of cyclooxygenase-2, ex...
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In vitro activity of ozenoxacin, a novel nonfluorinated topical (L. D. Saravolatz and J. Leggett, Clin. Infect. Dis. 37:1210-1215, 2003) quinolone, was compared with the activities of other quinolones against well-characterized quinolone-susceptible and quinolone-resistant Gram-positive bacteria. Ozenoxacin was 3-fold to 321-fold more active than other quinolones. Ozenoxacin could represent a f...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2020
ISSN: 0021-8820,1881-1469
DOI: 10.1038/s41429-020-0278-5